After ingestion of a corrosive chemical or mixture, endoscopy should be performed to determine the severity of the injury. One method of grading the severity of injury is modeled after the classification of thermal burns to the skin.
The endoscopic evaluation should be done to include both the entire esophagus and stomach, since burns can be multifocal with different severities.
Pathologic stages:
(1) First degree burn: superficial involvement of the mucosa.
(2) Second degree: transmucosal involvement with or without involvement of the muscularis. No extension into periesophageal or perigastric tissue.
(3) Third degree: full thickness injury with extension into the periesophageal or perigastric tissue. Adjacent organs (intestine, pancreas, liver, spleen, mediastinal structures) may be involved.
Finding |
First Degree |
Second Degree |
Third Degree |
bleeding |
hyperemia without bleeding |
mild to moderate bleeding |
moderate to severe bleeding |
edema |
mild |
moderate |
severe |
mucosal loss |
may involve the superficial layers of the mucosa |
mucosal ulceration, blistering |
deep ulcerations with possible perforation |
exudate |
none |
present with pseudomembrane |
present with pseudomembrane |
appearance if endoscopy delayed |
none |
granulation tissue |
eschar formation |
Specialty: Toxicology, Emergency Medicine, Critical Care, Gastroenterology