In diabetics the mean daily plasma glucose can be estimated from the glycohemoglobin level.
Based on Total Glycohemoglobin (Wallach)
estimated mean daily plasma glucose (mg/dL) =
= (10 * ((total glycohemoglobin A1 level in percent) + 4)) =
= (10 * (total glycohemoglobin A1 level in percent)) + 40
where:
• total glycohemoglobin A1 = A1a + A1b + A1c
• normal total glycohemoglobin: 4-8%
• The equation is applicable for total glycohemoglobin A1 levels between 4-20%.
Based on Hemoglobin A1c Alone
Hemoglobin A1c in Percent |
Whole Blood Glucose in mg/dL |
6% |
120 |
7% |
150 |
8% |
180 |
9% |
210 |
10% |
240 |
11% |
270 |
12% |
300 |
13% |
330 |
14% |
360 |
If this data is modeled in JMP:
whole blood glucose in mg/dL =
= (30 * (percent HgbA1c as a whole number)) - 60
American Diabetes Association (ADA) Equations
The formulae recommended by the ADA are based on the A1c-Derived Daily Glucose (ASAG) study:
estimated average glucose in mg/dL =
= (28.7 * (percent hemoglobin A1c)) - 46.7
estimated average glucose in mmol/L =
= (1.59 * (percent hemoglobin A1c)) - 2.59
Purpose: To estimate a diabetic patient's glucose concentration based on the glycohemoglobin level.
Specialty: Endocrinology, Clinical Laboratory
Objective: laboratory tests
ICD-10: R73.9, E16.2,