Since a child's development varies from the adult, with different muscle mass and renal function, distinct equations for children are appropriate.
Method of Counahan et al.
estimated glomerular filtration rate in mL pre min per 1.73 meters squared =
= (0.43 * (height in cm) / ((plasma creatinine in mg/dL) - (0.14 mg/dL for noncreatinine chromogens)))
This was rewritten by Swinkels et al (2000) for SIU as:
estimated glomerular filtration rate in mL pre min per 1.73 meters squared =
= (38.05 * (height in cm) / (plasma creatinine in µmol/L))
Method of Dechaux et al
estimated creatinine clearance in mL/min per 1.73 meters squared =
= ((0.52 * (height in cm)) / (serum creatinine in mg/dL)) - 3.6
Method in Rowland
creatinine clearance in mL/min =
= (0.48 * (height in cm)) * (((weight in kg) / 70)^0.7) / (serum creatinine in mg/dL)
where:
• This assumes a normal weight for height; body weight is the adjusted body mass (use ideal body weight if current body weight exceeds the ideal body weight, else use the current body weight)
• The equation applies for an age range 1 - 20 years.
Method of Schwartz et al (1976)
creatinine clearance in mL/min per 1.73 meters squared =
= (0.55 * (height in cm)) / (serum creatinine in mg/dL)
where:
• The method of Schwartz et al tends to overestimate the true GFR especially when the GFR is low. The method was developed when the Jaffe reaction was used to measure creatinine; this reported higher creatinine values than the current enzymatic methods.
Method of Schwartz et al (1984) for Infants < 12 Months
creatinine clearance in mL/min per 1.73 meters squared =
= (0.45 * (height in cm)) / (serum creatinine in mg/dL)
Method of Schwartz et al (1985) for Adolescent Boys
creatinine clearance in mL/min per 1.73 meters squared =
= (1.5 * (age in years)) + (0.5 * (height in cm) / (serum creatinine in mg/dL))
Method of Shull et al
ER = creatinine excretion rate in mg/min per 1.73 meters squared =
= (0.035 * (age)) + 0.236
creatinine clearance in mL/min per 1.73 meters squared =
= (ER) * 100 / (serum creatinine in mg/dL)
