Estrogen therapy may be associated with pancreatitis in some patients.
Features:
(1) onset of pancreatitis following the start of estrogen therapy
(2) resolution after estrogen withdrawal
(3) exclusion of other causes
(4) recurrence on re-exposure to estrogen
(5) severe hypertriglyceridemia (presumably with increased chylomicrons)
where:
• Seo et al reference a case affecting a fetus.
• Some patients may have genetic lipoprotein lipase deficiency.
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Specialty: Gastroenterology