The European League Against Rheumatism (EULAR) developed criteria for evaluating the therapeutic response in a patient with rheumatoid arthritis.
Parameters:
(1) measure of disease activity before therapy
(2) measure of disease activity after therapy (using the same measure as before therapy)
Measures of disease activity:
(1) DAS
(2) DAS28
change in disease activity after therapy vs before =
= (measure of disease activity after therapy) - (measure of disease activity before therapy)
A change > 1.2 is considered a significant change.
Response Criteria Using DAS
|
Current Score |
Difference in scores |
Response |
|---|---|---|
|
<= 2.4 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
moderate response |
|
|
> 1.2 |
good response |
|
2.41 to 3.7 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
moderate response |
|
|
> 1.2 |
moderate response |
|
> 3.7 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
no response |
|
|
> 1.2 |
moderate response |
where:
• A DAS < 2.6 indicates being in remission using the ARA criteria.
Response Criteria Using DAS28
|
Current Score |
Difference in scores |
Response |
|---|---|---|
|
<= 3.2 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
moderate response |
|
|
> 1.2 |
good response |
|
3.21 to 5.1 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
moderate response |
|
|
> 1.2 |
moderate response |
|
> 5.1 |
<= 0.6 |
no response |
|
|
0.61 to 1.2 |
no response |
|
|
> 1.2 |
moderate response |
Purpose: To evaluate the therapeutic response of a patient with rheumatoid arthritis using the EULAR response criteria.
Specialty: Immunology/Rheumatology
Objective: severity, prognosis, stage, response to therapy, disease progression
ICD-10: M05, M06,
