Kremers et al reported the upper limit of normal (95th percentile) for sclerotic glomeruli in a renal biopsy based on the age of the patient. A number of sclerotic glomeruli that exceeds this cannot explained by aging alone. The authors are from the Mayo Clinic and Cleveland Clinic.
Parameters:
(1) age in years, from 18 to 77
(2) number of glomeruli in the renal biopsy, from 1 to 64
Upper limit of normal for sclerotic glomeruli for age
Age in years |
1 glomerulus |
2 glomeruli |
3 or 4 glom |
5 to 8 glom |
18 to 29 |
0.5 |
0.5 |
0.5 |
0.5 |
30 to 34 |
0.5 |
0.5 |
0.5 |
0.5 |
35 to 39 |
0.5 |
0.5 |
0.5 |
0.5 |
40 to 44 |
0.5 |
0.5 |
0.5 |
1 |
45 to 49 |
0.5 |
0.5 |
1 |
1 |
50 to 54 |
1 |
1 |
1 |
1.5 |
55 to 59 |
1 |
1 |
1.5 |
1.5 |
60 to 64 |
1 |
1.5 |
1.5 |
2 |
65 to 69 |
1 |
2 |
2 |
2.5 |
70 to 74 |
1 |
2 |
2.5 |
3 |
75 to 77 |
1 |
2 |
2.5 |
3 |
Age in years |
9 to 16 glom |
17 to 32 glom |
33 to 48 glom |
49 to 64 glom |
18 to 29 |
1 |
1 |
1 |
1 |
30 to 34 |
1 |
1 |
1 |
1.5 |
35 to 39 |
1 |
1.5 |
2 |
2 |
40 to 44 |
1 |
2 |
2.5 |
3 |
45 to 49 |
1.5 |
2 |
3 |
4 |
50 to 54 |
2 |
3 |
4 |
5 |
55 to 59 |
2 |
3.5 |
4.5 |
6 |
60 to 64 |
2.5 |
4 |
5.5 |
7 |
65 to 69 |
3 |
4.5 |
6.5 |
8 |
70 to 74 |
4 |
5.5 |
7.5 |
9 |
75 to 77 |
5 |
6 |
8 |
9.5 |
Specialty: Nephrology