Niewoehner et al developed a score for predicting exacerbations in a patient with chronic obstructive pulmonary disease (COPD). This can help identify a patient who may benefit from more aggressive management. The authors are from multiple Veterans Affairs hospitals across the United States.
Parameters:
(1) age of the patient in years
(2) observed FEV1 as percent of predicted
(3) productive cough
(4) theophylline therapy at entry
(5) duration of COPD in years
(6) course of antibiotics for COPD during the prior year
(7) number of courses of systemic steroids for COPD during the prior year
(8) hospital admissions for COPD during the prior year
Parameter |
Finding |
Points |
---|---|---|
age of the patient in years |
< 45 years |
0 |
|
45 to 54 years |
20 |
|
55 to 64 years |
40 |
|
65 to 74 years |
60 |
|
75 to 84 years |
80 |
|
>= 85 years |
100 |
FEV1 as percent of predicted |
10 to 19% |
75 |
|
20 to 29% |
66 |
|
30 to 39% |
56 |
|
40 to 49% |
47 |
|
50 to 59% |
38 |
|
60 to 69% |
28 |
|
>= 70% |
0 |
productive cough |
absent |
0 |
|
present |
31 |
theophylline therapy at entry |
no |
0 |
|
yes |
26 |
duration of COPD |
1 year |
0 |
|
2 years |
5 |
|
3 years |
9 |
|
4 years |
14 |
|
5 years |
19 |
|
6 years |
23 |
|
7 years |
28 |
|
>= 8 years |
33 |
course of antibiotics for COPD |
0 |
0 |
|
>= 1 |
63 |
courses of systemic steroids |
0 |
0 |
|
1 |
39 |
|
>= 2 |
70 |
hospital admissions |
0 |
0 |
|
>= 1 |
24 |
where:
• An FEV1 < 10% of predicted is probably incompatible with life. An FEV1 >= 70% of predicted can be handled in several ways. For the implementation I set it to 0.
total score =
= SUM(points for all 8 parameters)
Interpretation:
• minimum score: 0
• maximum score: 422
• The higher the score the greater the risk of an exacerbation of the COPD.
Total Score |
Percent probability of an exacerbation within 6 months |
---|---|
< 50 |
< 7% |
50 to 250 |
(0.000444 * ((points)^2)) + (0.01629 * (points)) + 5.946 |
250 to 425 |
(-0.000148 * ((points)^2)) + (0.4008 * (points)) - 53.54 |
Purpose: To evaluate a patient with moderate to severe COPD for the risk of exacerbation using the score of Niewoehner et al.
Specialty: Pulmonology
Objective: risk factors, severity, prognosis, stage, complications, selection
ICD-10: J42, J43, J44,