Exercise-induced hyperventilation may result in a sense of chest tightness that can be clinically confused with exercise-induced asthma. The presence of clinical and pulmonary function findings can help distinguish these two conditions. The authors are from the University of Iowa.
Findings |
Exercise-Induced Asthma |
Exercise-Induced Hyperventilation |
symptoms associated with exercise |
wheezing, cough, chest tightness |
chest tightness |
history |
onset of respiratory disease in early childhood |
no history of respiratory disease in early childhood |
other causes inducing similar symptoms |
other stimuli usually present |
other stimuli usually absent |
response to an inhaled beta-2 agonist |
responds |
does not respond |
decrease in FEV1 after exercise |
> 15% |
< 15% |
decrease in end tidal carbon dioxide (ET CO2) after exercise |
< 15% |
>= 15% |
decrease in FEV1 after exercise in liters =
= ((FEV1 before exercise in liters) – (FEV1 after exercise in liters)) / (FEV1 before exercise in liters) * 100%
decrease in end tidal carbon dioxide after exercise in mm Hg =
= ((ET CO2 before exercise in mm Hg) – (ET CO2 after exercise in mm Hg)) / (ET CO2 before exercise in mm Hg) * 100%
where:
• A normal person shows < 15% change in FEV1 and < 15% change in ET CO2 with exercise.
• A person with mixed exercise-induced asthma and hyperventilation would have a > 15% drop in FEV1 and a >= 15% decrease in ET CO2.
Purpose: To evaluate a person for exercise-induced asthma or hyperventilation.
Specialty: Surgery, orthopedic, Immunology/Rheumatology, Pulmonology
Objective: differential diagnosis and mimics, red flags, exercise
ICD-10: J45.1, J45.9,