A high serum IgE concentration can result in a false-positive radioallergosorbent test (RAST).
A high serum IgE concentration can be encountered in some patients with parasitic infections and in patients with the hyper-IgE syndrome (HIES).
Findings:
(1) high serum IgE concentration (> 3,000 IU/mL)
(2) positive RAST test in the absence of clinical allergy to the target antigen OR all RAST results positive
(3) positive blank reactant chamber with no target antigen
A patient with these features should be evaluated by another method.
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Specialty: Clinical Laboratory, Obstetrics & Gynecology, Cardiology, Emergency Medicine, Critical Care
ICD-10: ,
