Liu et al reported a model for predicting significant fibrosis in a patient with chronic hepatitis B viral infection. The authors are from Guangxi Traditional Chinese Medicine University and Guangxi Medical University in China.
Patient selection: chronic hepatitis B (HBV)
Parameters:
(1) serum globulin in g/dL
(2) platelet count in 10^9/L
FS =
= 1.683 - (0.008 * (platelet count)) + (0.485 * (globulin))
which can be simplified to:
= 1.7 - (0.01 * (platelet count)) + (0.5 * (globulin))
FS Score
Median Value
F0 or F1
1.218
F2 or F3
1.480
F4 (cirrhosis)
2.085
Performance:
• The area under the ROC curve for F4 was 0.78.
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Specialty: Gastroenterology
