Flare Severity Score of Lockshin et al for Patients with Systemic Lupus Erythematosus

alopecia

none

0

moderate

1

marked

2

rash

none

0

moderate

1

marked

2

fever

<= 38°C

0

38.1 – 39°C

1

> 39.0°C

2

serositis

none

0

moderate

1

marked

2

arthralgias and/or arthritis

none

0

arthralgias

1

arthritis

2

mucosal ulcers

none

0

moderate

1

marked

2

neurologic events

none

0

moderate

1

marked

2

malaise

none

0

moderate

1

marked

2

fundi

none

0

moderate

1

marked

2

lymph nodes

none

0

moderate

1

marked

2

spleen

nonpalpable

0

palpable

2

miscellaneous finding

none

0

moderate

1

marked

2

ESR

<= 25 mm/h

0

26 – 75 mm/h

1

> 75 mm/h

2

anti-DNA antibody

none or low titer

0

moderate titer

1

high titer

2

complement

normal (>= 150 U/mL)

0

moderate decrease (101 – 150 U/mL)

1

marked decrease (<= 100 U/mL)

2

creatinine

< 0.2 mg/dL

0

0.2 – 1.0 mg/dL

1

> 1.0 mg/dL

2

urine RBCs

0 – 3 per hpf (high power field)

0

4 – 10 per hpf

1

> 10 per hpf

2

urine protein

0, or <= 0.3 g per 24 h

0

trace to 2+, or 0.31 – 2.0 g per 24 h

1

3+ to 4+, or > 2.0 g per 24 h

2

hemoglobin

>= 13 g/dL

0

10.0 – 12.9 g/dL

1

< 10.0 g/dL

2

platelet count

>= 150,000 per µL

0

50,000 – 149,999 per µL

1

< 50,000 per µL

2