Gamma-Glutamyl Transpeptidase (GGT) to Platelet Count Ratio (GPR) and Hepatic Fibrosis

The GGT increases with hepatic injury while the platelet count decreases with splenomegaly.

Parameters:

(1) serum GGT in IU/L

(2) platelet count in 10^9/L

GGT to platelet ratio =

= (serum GGT) / (platelet count)

Interpretation:

• A ratio > 0.56 is associated with F4 liver fibrosis.

• A ratio > 0.32 is associated with F2 to F4 fibrosis.

Performance:

• The reference method for determining hepatic fibrosis impacts the accuracy of the prediction.