Kim et al proposed 2 noninvasive models for predicting cirrhosis in patients with chronic hepatitis B. The authors are from Yonsei University, Liver Cirrhosis Clinical Research Center (Seoul(, and Ajou University in Korea.
NOTE: Giannini et al reported the Platelet Count to Spleen Diameter Ratio (see Chapter 10).
Parameters:
(1) age in years
(2) platelet count in 10^9/L
(3) spleen size in cm (maximum longitudinal dimension seen on ultrasonography)
Age in Years |
Points |
0 to 29 |
0 |
30 to 39 |
1 |
40 to 49 |
2 |
50 to 59 |
3 |
60 to 69 |
4 |
>= 70 |
5 |
spleen platelet ratio index (SPRI) =
= (size of spleen in cm) / (platelet count in 10^(9) * 100
where:
• The platelet count value is the factor used to multiple 10^9.
age-spleen-platelet ratio index (ASPRI) =
= (points for age) + SPRI
Interpretation:
• minimum ASPRI: < 1
• maximum ASPRI: > 100
• An ASPRI < 5 excludes cirrhosis.
• An ASPRI > 12 indicates cirrhosis.
Performance:
• The positive predictive value for an ASPRI > 12 was 96%.
Purpose: To predict cirrhosis in a patient with chronic hepatitis B using the SPRI and ASPRI scores for Kim et al.
Specialty: Gastroenterology, Infectious Diseases
Objective: risk factors, laboratory tests, disease progression
ICD-10: K74.6, B18.0, B18.1,