Patient selection: woman with unprovoked venous thromboembolism who has been receiving oral anticoagulants for 5-7 months with no recurrence while on therapy
Component of the HERDOO2 score:
(1) HER for post-thrombotic signs of hyperpigmentation, edema, redness of either leg
(2) D for D-Dimer using the Vidas D-dimer test (bio-Merieux)
(3) for obesity based on body mass index (BMI)
(4) for older age
|
Parameter
|
Finding
|
Points
|
|
HER findings
|
absent
|
0
|
|
|
present
|
1
|
|
D-dimer
|
< 250 µg/L
|
0
|
|
|
>= 250 µg/L
|
1
|
|
body mass index
|
< 30 kg per square meter
|
0
|
|
|
>= 30 kg per square meter
|
1
|
|
age
|
< 65 years
|
0
|
|
|
>= 65 years
|
1
|
score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
• The higher the score the greater the need to continue oral anticoagulant therapy.
• A patient with a score of 0 or 1 may be able to discontinue anticoagulant therapy.
X =
= (1.2977 * (points for BMI)) + (0.6473 * (points for HER)) + (0.9155 * (points for D-dimer)) + (0.8084 * (points for age)) –3.9717
probability of recurrent venous thromboembolism =
= 1 / (1 + EXP((-1) * X))
