Description

A patient with sickle anemia may have right-to-left shunting which can increase during sickle-related exacerbations.


Patient selection: sickle cell anemia

 

Analysis: bubble echocardiography

 

A right-to-left shunt may be associated with:

(1) patent foramen ovale

(2) intrapulmonary

 

Flow through the shunt may increase during:

(1) acute chest syndrome

(2) vaso-occlusive crisis

(3) pneumonia

 

The patient may experience transient hypoxia during episodes of increased shunt flow.

 

Differential diagnosis of hypoxia:

(1) pulmonary embolism

(2) pneumonia

(3) acute chest syndrome


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