Spyropoulos et al evaluated hospitalized medical patients for the risk of venous thromboembolism (VTE). They developed a model that can be used to identify patients who may benefit from more aggressive management. The study was performed by the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) investigators.
Mnemonic: IMPACTILL
Term |
Parameter |
---|---|
IM |
immobilized |
P |
previous VTE |
A |
age |
C |
cancer |
T |
thrombophilia |
I |
ICU or CCU stay |
LL |
lower limb paralysis |
Parameter |
Finding |
Points |
---|---|---|
immobilization |
none or < 7 days |
0 |
|
>= 7 days |
1 |
history of thromboembolism |
no |
0 |
|
yes |
3 |
age of the patient in years |
<= 60 years of age |
0 |
|
> 60 years of age |
1 |
current cancer |
no |
0 |
|
yes |
2 |
known thrombophilia |
no |
0 |
|
yes |
2 |
ICU or CCU stay |
no |
0 |
|
yes |
1 |
lower limb paralysis |
no |
0 |
|
yes |
2 |
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 12
• The higher the score the greater the risk of venous thromboembolism within the next 3 months.
Score |
Observed VTE |
Observed Pulmonary Emboli (Half VTE) |
0 or 1 |
<= 0.6% |
0.3% |
2 or 3 |
1.5% |
0.6 to 0.8% |
4 |
4.8% |
2.8% |
5 to 10 |
8% |
3.8% |
Purpose: To predict the risk of venous thromboembolism (VTE) in a medical patient using the IMPACTILL model of Spyropoulos et al.
Specialty: Hematology Oncology, Clinical Laboratory
Objective: risk factors, criteria for diagnosis
ICD-10: I80, I81, I82, O22, O87,