Incalzi et al reported an index combining age and comorbid conditions. The authors are from the Universita Cattolica del Sacro Cuore in Rome and Cittadella della Carita in Taranto, Italy.
Parameters: see table
Parameter |
Finding |
Points |
---|---|---|
age in years |
< 76 years |
0 |
|
76 to 85 years |
2 |
|
86 to 95 years |
3 |
|
> 95 years |
4 |
chronic lymphocytic leukemia |
absent |
0 |
|
Stage A or B |
2 |
|
Stage C |
6 |
multiple myeloma |
absent |
0 |
|
stage I |
2 |
|
stage II |
4 |
|
stage III |
6 |
Hodgkin's disease |
absent |
0 |
|
Stage I or II |
2 |
|
Stage III |
6 |
congestive heart failure (CHF) |
absent |
0 |
|
NYHA I or II |
1 |
|
NYHA III or IV |
4 |
renal failure |
absent |
0 |
|
mild to moderate |
1 |
|
severe |
4 |
decubitus ulcer |
absent |
0 |
|
Stage 1 or 2 |
1 |
|
Stage 3 |
4 |
chronic myelogenous leukemia |
absent |
0 |
|
early stage |
2 |
|
blast crisis |
6 |
chronic lung disease |
absent |
0 |
|
COPD |
1 |
|
chronic failure, Stage I |
2 |
|
chronic failure, Stage II or III |
4 |
cancer |
absent |
0 |
|
localized disease |
2 |
|
metastatic |
4 |
|
peritoneal carcinomatosis |
6 |
diabetes mellitus |
absent |
0 |
|
without organ damage |
1 |
|
with organ damage |
2 |
dementia |
absent |
0 |
|
without anorexia, akinesia, dysphagia, decubiti |
1 |
|
with complications |
4 |
Parkinson's disease |
absent |
0 |
|
present without complications |
1 |
|
with complications |
4 |
liver disease |
absent |
0 |
|
mild, including steatosis |
1 |
|
chronic active hepatitis |
4 |
|
cirrhosis |
4 |
pancreatitis |
absent |
0 |
|
chronic |
1 |
|
acute |
2 |
cerebrovascular disease |
absent |
0 |
|
TIA |
1 |
|
ischemic stroke |
2 |
|
parenchymous hemorrhages |
6 |
collagen vascular disease |
absent |
0 |
|
early stage |
1 |
|
with organ damage |
4 |
anemia |
absent |
0 |
|
mild (hemoglobin < 10 g/dL) |
1 |
|
aplastic anemia with transfusions at intervals > 20 days |
2 |
|
aplastic anemia with transfusions at intervals <= 20 days |
4 |
non-Hodgkin's lymphoma |
absent |
0 |
|
present |
6 |
acute leukemia |
absent |
0 |
|
present |
6 |
sepsis |
absent |
0 |
|
present |
4 |
pulmonary thromboembolism |
absent |
0 |
|
past history of |
1 |
|
present |
4 |
infectious endocarditis |
absent |
0 |
|
present |
4 |
meningitis or encephalitis |
absent |
0 |
|
present |
4 |
multiple sclerosis |
absent |
0 |
|
present |
2 |
myasthenic gravis |
absent |
0 |
|
early disease |
2 |
hypertension |
absent |
0 |
|
present |
1 |
peripheral arterial disease |
absent |
0 |
|
present |
1 |
peptic ulcer disease |
absent |
0 |
|
present |
1 |
idiopathic inflammatory bowel disease (Crohn's, UC) |
absent |
0 |
|
present |
1 |
thyroid disease |
absent |
0 |
|
present (hyper or hypo) |
1 |
where:
• Collagenosis was interpreted as meaning collagen vascular disease.
• A number of items could have additional entries (such as myasthenia).
comorbidity index without age =
= SUM(points for all items other than age)
comorbidity index with age =
= (index without age) + (points for age)
Interpretation:
• minimum score: 0
• maximum score: > 50
• The higher the score the more severe the comorbidity.
• An age-comorbidity index > 7 was associated with an increased risk of mortality.
Purpose: To determine a patient's level of comorbidity using the index of Incalzi et al.
Objective: comorbid conditions
ICD-10: ,