Criteria for Evaluating a Patient for Hypercoagulability
A single episode of idiopathic venous thromboembolism, especially if the episode occurs in the absence of recent major surgery, trauma, prolonged immobilization or metastatic carcinoma.
plus
One or more of the following:
(1) recurrent episodes of venous thromboembolism
(2) massive venous thrombosis
(3) thrombosis in an unusual site (mesenteric vein, cerebral vein, etc.)
(4) thrombosis occurring at a young age (< 50 years) without an inducing cause
(5) a family history of thromboembolism (in 1 or more first or second degree relatives)
Additional clinical findings suggestive of hypercoagulability
(1) in women, a history of unexplained fetal wastage
(2) recurrent pulmonary embolism
(3) anticoagulant failure
