Luca et al reported the integrated MELD score (iMELD) for evaluating a patient with cirrhosis. Both age and hyponatremia are associated with mortality in patients with cirrhosis. The authors are from multiple institutions in Europe.
Parameters:
(1) MELD (modified)
(2) age in years
(3) sodium in mmol/L
iMELD =
= (MELD) + (0.3 * ((age)) - (0.7 * (sodium)) + 100
Interpretation:
• minimum score: around 0 (the 100 was added to avoid negative numbers)
• maximum score: around 100
Performance:
• The iMELD was a better predictor of mortality than the MELD score.
• For patients undergoing elective TIPS, the area under the ROC curve for 12 month mortality was 0.78
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Specialty: Gastroenterology
