Organs evaluated:
(1) liver
(2) bone marrow
(3) lung
Dysfunction is present:
(1) if the person meets the criteria listed for the organ, AND
(2) if the change is due to the histiocytosis X rather than therapy or other cause
Criteria for hepatic dysfunction - 0ne or more of the following:
(1) total protein < 5.5 g/dL
(2) albumin < 2.5 g/dL
(3) total bilirubin > 1.5 mg/dL without hemolysis
(4) edema
(5) ascites
Criteria for hematopoietic dysfunction - one or more of the following:
(1) hemoglobin < 10 g/dL in the absence of iron deficiency
(2) WBC count < 4,000 per µL
(3) absolute neutrophil count < 1,500 per µL
(4) platelet count < 100,000 per µL
Criteria for pulmonary dysfunction - one or more of the following:
(1) tachypnea
(2) dyspnea
(3) cyanosis
(4) cough
(5) pneumothorax
(6) pleural effusion
