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Hepatitis C Virus (HCV) Infection | Model for Predicting Posttransplant Survival

Purpose: To compare survival after liver transplantation for 2 patients with hepatitis C virus (HCV) using the model of Ghobrial et al.

Description

Ghobrial et al developed a model for predicting survival of a patient after liver transplantation for viral hepatitis C (HCV). This can be used to compare relative survival between two transplant recipients. The authors are from the University of California in Los Angeles.


 

Parameters:

(1) recipient's age in years

(2) recipient's serum creatinine in mg/dL

(3) donor's gender

(4) UNOS status (see 11.11.04)

 

Parameter

Finding

Points

donor's gender

male

0

 

female

1

UNOS status

not urgent

0

 

urgent

1

 

death index for recipient X vs recipient Y =

= (0.0293 * ((age recipient X) - (age recipient Y))) + (1.085 * (LOG10(recipient X creatinine) - LOG10(recipient Y creatinine))) + (0.289 * ((gender points donor X) - (gender points donor Y))) + (0.675 * ((UNOS points recipient X) - (UNOS points recipient Y))) - (1.612 * ((LOG10(recipient X creatinine) * (UNOS points recipient X)) - (LOG10(recipient Y creatinine) * (UNOS points recipient Y))))

 

relative risk of death of recipient X vs recipient Y =

= EXP(death index)

 


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Specialty

Objective

ICD-10