Description

Evaluation of a lupus patient using the BILAG (British Isles Lupus Assessment Group) index can help to identify a patient experiencing a flare in disease activity.


 

Systems evaluated with the revised BILAG index:

(1) constitutional

(2) mucocutaneous

(3) neuropsychiatric

(4) musculoskeletal

(5) cardiorespiratory

(6) gastrointestinal

(7) renal

(8) hematological

(9) ophthalmic

Disease Activity

Designation

marked activity

A

moderate activity

B

mild and stable activity

C

inactivity

D

no activity ever

E

 

 

Change in BILAG Index

Significance

Therapy

appearance of 1 or more A scores

flare indicating severe disease

usually new or increased therapy with cortico-steroids and/or cytotoxic agents.

appearance of 1 or more B scores

flare with less severe disease

may or may not receive new or increased doses of disease-modifying therapy

other

not considered a flare

continue to monitor the patient; therapy may be reduced if all scores decline

 

A patient with one or more new B scores may not receive additional therapy if:

(1) the patient is already under treatment

(2) the process is expected to be self-limited (for example, triggered by a viral infection)

(3) physician waiting for more results before deciding whether or not to treat

 


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