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Malaria Prognosis Score (MPS) of Mishra et al for Predicting Mortality in an Adult with Severe Falciparum Malaria

Purpose: Purpose: To evaluate an adult with severe falciparum malaria using the Malaria Prognostic Score (MPS) of Mishra et al.

Description

Mishra et al developed the Malaria Prognosis Score (MPS) for predicting mortality in an adult with severe falciparum malaria. This can help identify a patient who may benefit from more aggressive management. The authors are from Ispat General Hospital (India), Sushilavati Government Women's College (India) and the University of Maryland in Baltimore.


Patient selection: adult with falciparum malaria

 

Parameters:

(1) severe anemia

(2) acute renal failure

(3) acute respiratory distress (ARDS)

(4) cerebral malaria (with unrousable coma)

 

Parameter

Finding

Points

severe anemia

absent (hemoglobin >= 5 g/dL)

0

 

present (hemoglobin < 5 g/dL)

1

acute renal failure

absent

0

 

present (serum creatinine > 3 mg/dL)

2

respiratory distress with need for mechanical ventilation

absent

0

 

present

3

cerebral malaria

absent

0

 

present (unrousable coma)

4

 

malaria prognosis score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the greater the risk of mortality.

 

MPS

Risk Group

Mortality Rate

0, 1 or 2

low

2%

3 or 4

low to moderate

10%

5 or 6

moderate

40%

7 to 10

high

90%

 


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Specialty

Objective

ICD-10