Common lymphoproliferative disorders:
(1) immunoblastic lymphoma
(2) other diffuse large B-cell lymphoma
(3) Burkitt’s lymphoma
Less common disorders:
(1) Hodgkin’s disease
(2) T-cell chronic lymphocytic leukemia (CLL)
Rare disorders:
(1) primary effusion lymphoma (body cavity based lymphoma or BCBL)
(2) plasmablastic lymphoma associated with multi-centric Castleman’s disease
(3) plasmablastic lymphoma not associated with Castleman’s disease
(4) primary lymphoma of the brain
These tumors may show a variety lf genetic lesions including:
(1) Epstein-Barr virus (EBV)
(2) c-myc gene rearrangement
(3) bcl-6 gene rearrangement
(4) ras gene mutations
(5) p53 mutations or deletions