Description

Vandromme et al reported risk factors associated with massive transfusion in a civilian trauma patient. The authors are from the University of Alabama at Birmingham.


 

Patient selection: civilian trauma

 

Parameters:

(1) blood lactate concentration

(2) heart rate in beats per minute

(3) INR

(4) hemoglobin in g/dL

(5) systolic blood pressure in mm Hg

 

Parameter

Finding

Points

blood lactate concentration

< 5 mmol/L

0

 

>= 5 mmol/L

1

heart rate

<= 105 beats per minute

0

 

> 105 beats per minute

1

INR

<= 1.5

0

 

> 1.5

1

hemoglobin

>= 11 g/dL

0

 

< 11 g/dL

1

systolic blood pressure

>= 110 mm Hg

0

 

< 110 mm Hg

1

 

number of risk factors =

= SUM(points for all 5 parameters)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 5

• The need for massive transfusion tended to increase with the number of risk factors present.

 

Performance:

• The presence of 1 or more risk factors was 96% sensitive and 60% specific.

• The presence of 3 or more risk factors was 60% sensitive and 96% specific.

• The maximum Youden index is with >= 2 risk factors (63%).

 


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