Vandromme et al reported risk factors associated with massive transfusion in a civilian trauma patient. The authors are from the University of Alabama at Birmingham.
Patient selection: civilian trauma
Parameters:
(1) blood lactate concentration
(2) heart rate in beats per minute
(3) INR
(4) hemoglobin in g/dL
(5) systolic blood pressure in mm Hg
Parameter |
Finding |
Points |
blood lactate concentration |
< 5 mmol/L |
0 |
|
>= 5 mmol/L |
1 |
heart rate |
<= 105 beats per minute |
0 |
|
> 105 beats per minute |
1 |
INR |
<= 1.5 |
0 |
|
> 1.5 |
1 |
hemoglobin |
>= 11 g/dL |
0 |
|
< 11 g/dL |
1 |
systolic blood pressure |
>= 110 mm Hg |
0 |
|
< 110 mm Hg |
1 |
number of risk factors =
= SUM(points for all 5 parameters)
Interpretation:
• minimum number of risk factors: 0
• maximum number of risk factors: 5
• The need for massive transfusion tended to increase with the number of risk factors present.
Performance:
• The presence of 1 or more risk factors was 96% sensitive and 60% specific.
• The presence of 3 or more risk factors was 60% sensitive and 96% specific.
• The maximum Youden index is with >= 2 risk factors (63%).
Purpose: To evaluate a civilian trauma patient for risk factors associated with massive transfusion based on the study of Vandromme et al.
Specialty: Clinical Laboratory, Surgery, general, Anesthesiology, Emergency Medicine, Critical Care
Objective: risk factors
ICD-10: T79-T79,