Description

The rate of chromosomal abnormalities in newborn infants increase with increasing maternal age.


 

Rate of Chromosomal abnormalities per 100 live births (percent)

Maternal Age (years)

Total (in percent)

Down's Syndrome

Trisomy 13

Trisomy 18

XXY

< 15

0.22

0.10

<0.01-0.01

< 0.01

0.04

15

0.22

0.10

<0.01-0.01

< 0.01

0.04

16

0.21

0.09

<0.01-0.01

< 0.01

0.04

17

0.2

0.08

<0.01-0.01

< 0.01

0.04

18

0.19

0.07

<0.01-0.01

< 0.01

0.04

19

0.18

0.06

<0.01-0.01

< 0.01

0.04

20

0.19

0.05-0.07

<0.01-0.01

<0.01-0.01

0.04

21

0.19

0.05-0.07

<0.01-0.01

<0.01-0.01

0.04

22

0.2

0.06-0.08

<0.01-0.01

<0.01-0.01

0.04

23

0.2

0.06-0.08

<0.01-0.01

<0.01-0.01

0.04

24

0.21

0.07-0.09

<0.01-0.01

<0.01-0.01

0.04

25

0.21

0.07-0.09

<0.01-0.01

<0.01-0.01

0.04

26

0.21

0.07-0.10

<0.01-0.01

<0.01-0.01

0.04

27

0.22

0.08-0.10

<0.01-0.01

0.01-0.02

0.04

28

0.23

0.08-0.11

<0.01-0.02

0.01-0.02

0.04

29

0.24

0.08-0.12

<0.01-0.02

0.01-0.02

0.05

30

0.26

0.09-0.12

<0.01-0.02

0.01-0.02

0.05

31

0.26

0.09-0.13

<0.01-0.02

0.01-0.02

0.05

32

0.31

0.11-0.15

0.01-0.02

0.01-0.02

0.06

33

0.35

0.14-0.19

0.01-0.02

0.01-0.03

0.07

34

0.41

0.19-0.24

0.01-0.03

0.02-0.04

0.07

35

0.56

0.25-0.39

0.02-0.03

0.03-0.05

0.09

36

0.67

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