The rate of chromosomal abnormalities in newborn infants increase with increasing maternal age.
Rate of Chromosomal abnormalities per 100 live births (percent)
Maternal Age (years) |
Total (in percent) |
Down's Syndrome |
Trisomy 13 |
Trisomy 18 |
XXY |
< 15 |
0.22 |
0.10 |
<0.01-0.01 |
< 0.01 |
0.04 |
15 |
0.22 |
0.10 |
<0.01-0.01 |
< 0.01 |
0.04 |
16 |
0.21 |
0.09 |
<0.01-0.01 |
< 0.01 |
0.04 |
17 |
0.2 |
0.08 |
<0.01-0.01 |
< 0.01 |
0.04 |
18 |
0.19 |
0.07 |
<0.01-0.01 |
< 0.01 |
0.04 |
19 |
0.18 |
0.06 |
<0.01-0.01 |
< 0.01 |
0.04 |
20 |
0.19 |
0.05-0.07 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
21 |
0.19 |
0.05-0.07 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
22 |
0.2 |
0.06-0.08 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
23 |
0.2 |
0.06-0.08 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
24 |
0.21 |
0.07-0.09 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
25 |
0.21 |
0.07-0.09 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
26 |
0.21 |
0.07-0.10 |
<0.01-0.01 |
<0.01-0.01 |
0.04 |
27 |
0.22 |
0.08-0.10 |
<0.01-0.01 |
0.01-0.02 |
0.04 |
28 |
0.23 |
0.08-0.11 |
<0.01-0.02 |
0.01-0.02 |
0.04 |
29 |
0.24 |
0.08-0.12 |
<0.01-0.02 |
0.01-0.02 |
0.05 |
30 |
0.26 |
0.09-0.12 |
<0.01-0.02 |
0.01-0.02 |
0.05 |
31 |
0.26 |
0.09-0.13 |
<0.01-0.02 |
0.01-0.02 |
0.05 |
32 |
0.31 |
0.11-0.15 |
0.01-0.02 |
0.01-0.02 |
0.06 |
33 |
0.35 |
0.14-0.19 |
0.01-0.02 |
0.01-0.03 |
0.07 |
34 |
0.41 |
0.19-0.24 |
0.01-0.03 |
0.02-0.04 |
0.07 |
35 |
0.56 |
0.25-0.39 |
0.02-0.03 |
0.03-0.05 |
0.09 |
36 |
0.67 |
SpecialtyInfoSpecialty: Obstetrics & Gynecology |