The mean residence time is the average time that molecules of a drug reside in the body after a dose.
mean residence time in hours =
= 1.44 * (half-life in hour) =
= (volume of distribution in L) / (clearance in L per hr)
half-life for the drug in hours =
= (mean residence time) / 1.44 = 0.693 * (mean residence time)
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Specialty: Toxicology, Emergency Medicine, Critical Care
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