Buettner et al developed a model for predicting one-year mortality following complex gastrointestinal surgery for a malignancy. This model uses sarcopenia as a surrogate marker for farilty. The authors are from the Johns Hopkins Hospital.
Patient selection: GI surgery (hepatobiliary, pancreatic, colorectal)
Outcome: 1-year mortality
Parameters:
(1) age in years
(2) preoperative hemoglobin in g/dL
(3) ECOG performance status
(4) sarcopenia (based on total psoas muscle density by Hounsfield unit average calculation, HUAC. Sarcopenia for males < 39.9 HU and for females < 38.1)
Parameter |
Findings |
Points |
age in years |
<= 55 years |
0 |
|
56 to 65 years |
2.5 |
|
66 to 75 years |
5.8 |
|
>= 76 years |
10 |
preoperative hemoglobin |
>= 12.5 g/dL |
0 |
|
< 12.5 g/dL |
5.1 |
ECOG |
0 |
0 |
|
1 to 4 |
3.6 |
sarcopenia |
Absent |
0 |
|
present |
6.7 |
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 25.4
• The higher the score the greater the 1-year mortality rate.
percent mortality at 1-year =
= (0.0647 * ((score)^2)) - (0.2595 * (score)) + 5.575
Performance:
• The area under the ROC curve was 0.70.
Specialty: Anesthesiology