Description

Dong et al reported a model for predicting the overall survival for a patient with a typical lung carcinoid tumor. This can help to identify a patient who may require more aggressive management. The authors are from Qingdao University and Peking University International Hospital in China.


Patient selection: typical lung carcinoid tumor

 

Parameters:

(1) bone metastases

(2) age in years

(3) sex

(4) T stage

(5) N stage

 

Parameter

Finding

Points

bone metastases

no

0

 

yes

38

age in years

< 62 years

0

 

62 to 77 years

44.3

 

> 77 years

100

sex

female

0

 

male

21.7

T stage

TX

51.6

 

T1

0

 

T2

20.2

 

T3

21.1

 

T4

24.4

N stage

N0

0

 

N1

32.6

 

N2

71

 

N3

81.3

 

NX

49.8

 

where:

• The nomogram shows a couple inconsistencies in the data on T stage. The point assignment above is based on the relative status of the hazard ratios shown in Figure 1.

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 270.9

• The higher the score the worse the overall survival.

 

value of X =

= (-0.00007125 * ((score)^2)) - (0.008283 * (score)) + 2.732

 

probability of 5-year overall survival =

= 1 / (1 + EXP((-1) * X))


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