Li et al reported a model for predicting iron deficiency in a plateletpheresis donor. This can help to identify a patient who may need iron replacement. The authors are from Zhejiang University, Blood Center of Zhejiang Province, Key Laboratory of Blood Safety Research Hangzhou and Key Laboratory of Precision Medicine.
Patient selection: plateletpheresis donor
Parameters:
(1) age in years
(2) sex
(3) hemoglobin in g/L
(4) MCHC in g/L
(5) RDW-CV in percent
(6) total number of blood donations
(7) number of donated blood components in the past year
Parameter
Finding
Points
age in years
-0.035 * (age)
sex
female
0
male
1.961
hemoglobin
-0.060 * (hemoglobin)
MCHC
-0.037 * (MCHC)
RDW-CV
0.345 * (RDW-CV)
total blood donations
0.008 * (number)
number of donated components this year
0.151 * (number)
value of X =
= SUM(points for all of the parameters) + 14.553
probability of iron deficiency =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.88.
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