Liao et al reported a simple score for predicting statin nonadherence in a patient who has just had an acute coronary syndrome (ACS). The authors are from University of Auckland and affiliated hospitals in New Zealand.
Outcome: nonadherence based on a Medication Possession Ratio (MPR) < 0.8.
Parameters:
(1) age of the patient
(2) sex
(3) ethnic group
(4) socioeconomic level
(5) smoking status
(6) revascularization
(7) combination of prior CVD, statin use, and serum LDL on admission
Parameter
Finding
Points
age of the patient
< 45 years
3
45 to 54 years
1
>= 55 years
0
sex
female
1
male
0
ethnic group
Maori or Pacific Islander
3
other
0
socioeconomic level
lowest 2 deciles
1
third to tenth deciles
0
smoking status
current
1
former or never
0
revascularization
no
3
yes
0
Prior CVD
Statin Use
Serum LDL
Points
no
no
NA
8
yes
no
NA
13
yes
yes
< 2.0 mmol/L
0
yes
yes
2.0-2.9 mmol/L
3
yes
yes
>= 3.0 mmol/L
7
yes
yes
unknown
2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 25
Total Score
Non-Adherence
0 to 2
10%
3 to 5
17%
6 to 8
23%
9 to 11
26%
12 to 14
16%
15 to 17
6%
>= 18
2%
Performance:
• The area under the ROC curve was 0.67.
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