Lin et al reported a simple score for early prediction of sepsis in an older adult. The authors are from Taipei Medical University.
Patient selection: age >= 60 years
Parameters:
(1) modified early warning score (MEWS)
(2) white blood cell count in 10^9/L
(3) neutrophil-to-lymphocyte ratio (NLR)
(4) monocyte distribution width (MDW), presumably in IU
Parameter
Finding
Points
MEWS
< 3
0
>= 3
1
WBC count
< 11 * 10^9/L
>= 11 * 10^9/L
NLR
< 8
>= 8
MDW
< 20
>= 20
2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• A score >= 3 had the highest Youden index.
Performance:
• The area under the ROC curve varied from 0.89 to 0.82 depending on age group.
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Specialty: Infectious Diseases