Malhame et al reported a score for predicting acute cardiovascular morbidity for a woman with preeclampsia. The authors are from multiple institutions in Canada and New England.
Patient selection: woman with preeclampsia
Acute cardiovascular morbidity: pulmonary edema or acute heart failure, acute myocardial infarction, arterial aneurysm, aortic dissection, cardiac arrest, stroke, TIA, central venous thrombosis, cardiogenic shock, need for cardioversion, difficult to control severe hypertension, etc)
Time period: from delivery admission to 6 weeks after hospital discharge
Parameters:
(1) maternal age in years
(2) maternal education in years
(3) number of previous live births
(4) previous cesarean section
(5) multiple gestation
(6) chronic hypertension
(7) gestational diabetes
(8) gestational age at delivery in weeks
|
Parameter
|
Finding
|
Beta-Coefficient
|
|
maternal age in years
|
< 21 years
|
-0.228
|
|
|
21 to 29 years
|
0
|
|
|
30 to 34 years
|
-0.024
|
|
|
35 to 39 years
|
0.402
|
|
|
>= 40 years
|
0.502
|
|
maternal education
|
high school or less
|
0
|
|
|
some postsecondary
|
-0.061
|
|
|
4-year college grad
|
-0.152
|
|
|
graduate or professional school
|
-0.712
|
|
previous live births
|
0
|
0
|
|
|
1
|
-0.562
|
|
|
>=2
|
-0.632
|
|
previous C-section
|
no
|
0
|
|
|
yes
|
0.382
|
|
multiple gestation
|
no
|
0
|
|
|
yes
|
-0.659
|
|
chronic hypertension
|
no
|
0
|
|
|
yes
|
-1.038
|
|
gestational diabetes
|
no
|
0
|
|
|
yes
|
-0.431
|
|
gestational age at delivery
|
20 to 36 weeks
|
1.679
|
|
|
37 to 38 weeks
|
0.558
|
|
|
39 to 40 weeks
|
0
|
|
|
41 to 44 weeks
|
-0.554
|
value of X =
= SUM(beta coefficients for all of the parameters) - 2.995
Performance:
• The area under the ROC curve is 0.72.
