Patient selection: age 60 days to 18 years with suspected sepsis
Exclusion: septic shock on arrival
Parameters:
(1) systolic blood pressure (SBP) in mm Hg
(2) diastolic blood pressure (DBP) in mm Hg
(3) temperature in °C
(4) age in years times respiratory rate in breaths per minute
(5) age in years times shock index (heart rate divided by SBP)
(6) arrival via Emergency Medical Services (EMS)
(7) cancer (oncologic comorbidity)
(8) indwelling central line present on arrival
(9) hospitalized in the past year
Parameter
|
Finding
|
Points
|
systolic blood pressure
|
|
-0.0228011 * (SBP)
|
diastolic blood pressure
|
>= 69 mm Hg
|
0
|
|
< 69 mm Hg
|
0.0235015 * (69 - (DBP))
|
temperature in °C
|
|
-0.056130 * (temp)
|
respiratory rate and age
|
|
0.0011637 * (age)* (RR)
|
shock index and age
|
|
0.064513 * (age) * (SI)
|
arrival via EMS
|
no
|
0
|
|
yes
|
0.1394753
|
cancer
|
no
|
0
|
|
yes
|
-0.7875011
|
central line
|
no
|
0
|
|
yes
|
-0.057997
|
hospitalized in past year
|
no
|
0
|
|
yes
|
-0.1473406
|
value of X =
= SUM(points for all of the parameters) + 1.6415501
probability of septic shock =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.79.