Description

Scott et al reported a model for predicting septic shock in a pediatric patient arriving at the hospital with suspected sepsis. The authors are from the University of Colorado, Children's Hospital Colorado, British Columbia Children's Hospital, and the University of British Columbia.


Patient selection: age 60 days to 18 years with suspected sepsis

Exclusion: septic shock on arrival

 

Parameters:

(1) systolic blood pressure (SBP) in mm Hg

(2) diastolic blood pressure (DBP) in mm Hg

(3) temperature in °C

(4) age in years times respiratory rate in breaths per minute

(5) age in years times shock index (heart rate divided by SBP)

(6) arrival via Emergency Medical Services (EMS)

(7) cancer (oncologic comorbidity)

(8) indwelling central line present on arrival

(9) hospitalized in the past year

 

Parameter

Finding

Points

systolic blood pressure

 

-0.0228011 * (SBP)

diastolic blood pressure

>= 69 mm Hg

0

 

< 69 mm Hg

0.0235015 * (69 - (DBP))

temperature in °C

 

-0.056130 * (temp)

respiratory rate and age

 

0.0011637 * (age)* (RR)

shock index and age

 

0.064513 * (age) * (SI)

arrival via EMS

no

0

 

yes

0.1394753

cancer

no

0

 

yes

-0.7875011

central line

no

0

 

yes

-0.057997

hospitalized in past year

no

0

 

yes

-0.1473406

 

value of X =

= SUM(points for all of the parameters) + 1.6415501

 

probability of septic shock =

= 1 / (1 + EXP((-1) * X))

 

Performance:

The area under the ROC curve is 0.79.


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