Tyson et al evaluated the outcomes for extremely premature infants. The authors are participants of the National Institute of Child Health and Human Development Neonatal Research Network
Gestational ages: 22 to 25 weeks (adjusted ages ranged from 18 to 22 months)
Parameters:
(1) birthweight in grams
(2) gender
(3) gestational age
(4) number of fetuses
(5) antenatal steroid therapy
Parameter
Finding
Points
gender
male
0
female
-0.4454
gestational age
22 weeks
1.5741
23 weeks
0.9598
24 weeks
0.4721
25 weeks
0
number of fetuses
1
-0.2582
2 or more
0
antenatal steroid therapy
none
0
given
-0.6062
X=
= (-0.005113 * (birthweight in grams)) + SUM(points for the other 4 parameters) + 3.39
probability of death =
= 1 / (1 + EXP((-1) * X))
Parameter
Finding
Points
gender
male
0
female
-0.5898
gestational age
22 weeks
1.6552
23 weeks
0.9644
24 weeks
0.4195
25 weeks
0
number of fetuses
1
-0.2751
2 or more
0
antenatal steroid therapy
none
0
given
-0.6233
Y =
= (-0.004941 * (birthweight in grams)) + SUM(points for the other 4 parameters) + 4.0874
probability of death or profound impairment =
= 1 / (1 + EXP((-1) * Y))
Parameter
Finding
Points
gender
male
0
female
-0.7407
gestational age
22 weeks
1.5181
23 weeks
0.9408
24 weeks
0.3554
25 weeks
0
number of fetuses
1
-0.3528
2 or more
0
antenatal steroid therapy
none
0
given
-0.6402
Z =
= (-0.005018 * (birthweight in grams)) + SUM(points for the other 4 parameters) + 5.0599
probability of death or neurodevelopmental impairment =
= 1 / (1 + EXP((-1) * Z))
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