Description

Christianen et al developed several predictive models for swallowing dysfunction following chemoradiation for head and neck cancer.  One model predicts physician rate swallowing dysfunction at 6 months after therapy. The authors are from University Medical Center Groningen and VU University Medical Center Amsterdam in The Netherlands.


Patient selection: head and neck cancer after chemoradiation

 

Outcome: physician-rated swallowing dysfunction at 6 months after therapy

 

Parameters:

(1) mean radiation dose superior pharyngeal constrictor muscle (PCM) in Gy

(2) mean radiation dose supraglottic larynx in Gy

 

X =

= (0.057 * (mean dose superior PCM)) + (0.037 * (mean dose supraglottic)) – 6.09

 

probability of swallowing dysfunction =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve was 0.80.


To read more or access our algorithms and calculators, please log in or register.