Dean et al identified risk factors for a poor quality of life in a patient with ankylosing spondylitis that are potentially modifiable. These can identify possible targets for interventions. The authors are from the University of Aberdeen.
Patient selection: ankylosing spondylitis
Independent predictors:
(1) moderate or severe fatigue (odds ratio 1.6)
(2) poor physical function (BASFI >= 4; odds ratio 3.5)
(3) chronic widespread pain (odds ratio 1.9)
(4) high disease activity (BASDAI >= 4; odds ratio 1.5)
(5) poor spinal mobility (BASMI >= 4; odds ratio 1.5)
The quality of life declines as the number of predictors increase.
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