Modification of DiGiorgio et al for the Surveillance Definition of Central Line-Associated Bloodstream Infection (CLABSI) for a Patient with a Hematologic Malignancy

Description

DiGiorgio et al modified the National Health and Safety Network (NHSN) definition of central line-associated bloodstream infection (CLABSI) in patients with hematologic malignancy. This is meant to avoid false positive diagnosis caused by a mechanism other than the catheter. The authors are from the Cleveland Clinic.

Premise: in a patient with a hematologic malignancy the presence of treatment-related mucositis, graft-versus-host disease (GVHD) or neutropenia makes the patient susceptible to certain infections independent of a central catheter.

Patient selection: patient who meets the NHSN definition of CLABSI

The modification is to not call the situation CLABSI in any of the following situations:

Infectious Agent(s)	Situation
viridans group Streptococcus	mucositis
Enterococcus, Enterobacteriaceae or Candida species	bone marrow transplant recipient with graft-versus-host disease of the GI tract
Enterococcus, Enterobacteriaceae or Candida species	neutropenia due to dose-intensive chemotherapy

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Modification of DiGiorgio et al for the Surveillance Definition of Central Line-Associated Bloodstream Infection (CLABSI) for a Patient with a Hematologic Malignancy

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