Wu et al reported a modified version of the LRINEC score for necrotizing fasciitis. The authors are from Hebei Medical University and the General Hospital of the Inner Mongolia Autonomous Region in China.
Patient selection: severe soft tissue infection
Parameters:
(1) high-sensitivity CRP in mg/L
(2) WBC count in 10^9/L
(3) fasting blood glucose in mmol/L
(4) serum creatinine in µmol/L
(5) hemoglobin in g/L
(6) serum sodium in mmol/L
(7) comorbid diabetes
(8) comorbid kidney disease
Parameter
Finding
Points
hs-CRP
<= 55 mg/L
0
> 55 mg/L
12
WBC count
<= 11.7 * 10^9/L
0
> 11.7 * 10^9/L
5
fasting blood glucose
<= 6.1 mmol/L
0
> 6.1 mmol/L
4
serum creatinine
<= 82 µmol/L
0
> 82 µmol/L
10
hemoglobin
>= 110 g/L
0
< 110 g/L
6
serum sodium
>= 135 mmol/L
0
< 135 mmol/L
7
comorbid diabetes
no
0
yes
3
comorbid renal disease
no
0
yes
8
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 55
• A score >= 17 was associated with necrotizing fasciitis (sensitivity 0.93 and specificity 0.87).
Performance:
• The area under the ROC curve is 0.94.
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