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Montreal Prognostic Score (MPS) of Gagnon et al for Advanced Non-Small Cell Lung Cancer (NSCLC)

Description

Gagnon et al reported the Montreal Prognostic Score (MPS) for a patient with advanced non-small cell lung cancer (NSCLC). This can help to determine the prognosis of the patient. The authors are from Universite Laval, McGill University, University and Hospital of Larissa.


Patient selection: non-small cell lung cancer, Stage III or IV

 

Outcome: median survival time in months

 

Parameters:

(1) stage

(2) serum C-reactive protein in mg/L

(3) serum albumin in g/L

(4) serum LDH in IU/L

(5) neutrophil to lymphocyte ratio (NLR)

 

Parameter

Finding

Points

stage

III

0

 

IV

3

CRP

<= 10 mg/L

0

 

> 10 mg/L

3

serum albumin

> 38 g/L

0

 

<= 38 g/L

2

serum LDH

<= 250 IU/L

0

 

> 250 IU/L

2

NLR

<= 4.5

0

 

> 4.5

3

 

total score =

= SUM(points for all 5 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 13

 

Total Score

Prognostic Group

Median Survival

0 to 3

1

18.2 months

4 to 12

2

8.2 months

13

3

2.5 months

 

Performance:

• The area under the ROC curve is 0.69.


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