Noninfectious, nonendocrine causes:
(1)
hepatic tumor
(2) thalassemia
(3) hypoxic ischemic injury
(4) drug
(5) hemophagocytic lymphohistiocytoma
Endocrine causes:
(1) growth hormone deficiency
(2) panhypopituitarism
(3) hypocorticolism
Infectious causes:
(1) viral hepatitis A (HAV)
(2) viral hepatitis B (HBV)
(3) hepatitis C virus (HCV)
(4) Herpes simplex virus (HSV)
(5) Human Herpes Virus (HHV) 6, 7, 8
(6) cytomegalovirus (CMV)
(7) enterovirus
(8) parvovirus
(9) rubella
(10) coxsackie virus
(11) adenovirus
(12) HIV
(13) syphilis
(14) toxoplasmosis
(15) bacterial infection
Cases can occur where the cause is not identified.