Wynn and Polin reported the neonatal sequential organ failure assessment (nSOFA) score to evaluate neonates with sepsis. The authors are from the University of Florida and Columbia University.
Patient selection: neonate with presumed infection
Parameters:
(1) intubation status
(2) SpO2 to FIO2 ratio
(3) number of inotropes
(4) systemic steroid therapy
(5) platelet count per µL
Intubation Status
SpO2 to FIO2 Ratio
Respiratory Points
not intubated
NA
0
intubated
>= 300
0
intubated
200 to 299
2
intubated
150 to 199
4
intubated
100 to 149
6
intuabated
< 100
8
Number of Inotropes
Systemic Steroids
Cardiovascular Points
0
no
0
0
yes
1
1
no
2
>= 2
no
3
1
yes
3
>= 2
yes
4
Platelet Count
Hematologic Points
>= 150,000 per µL
0
100,000 to 149,999
1
50,000 to 99,999
2
< 50,000 per µL
3
total score =
= (respiratory points) + (cardiovascular points) + (hematologic points)
Interpreation:
• minimum score: 0
• maximum score: 15
• A score > 4 is associated with increased mortality for very low birthweight neonates with late-onset sepsis.
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