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New Scoring System of Hou et al for Early Prediction of Sepsis in the Emergency Department

Description

Hou et al reported a simple score for early prediction of sepsis in a patient in the Emergency Department. This can identify a patient who may benefit from early initiation of a sepsis protocol. The authors are from Taipei Medical University in Taiwan.


Parameters:

(1) qSOFA score, from 0 to 3

(2) neutrophil to lymphocyte ratio (NLR)

(3) platelet to lymphocyte ratio (PLR)

(4) monocyte distribution width (MDW) in Units

 

Parameters

Findings

Points

qSOFA

0 or 1

0

 

> 1

1

NLR

<= 9

0

 

> 9

2

PLR

<= 210

0

 

> 210

1

MDW

<= 20

0

 

> 20

1

 

where:

• Thrombocytopenia (seen in severe sepsis) is associated with a low PLR.

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 5

• A score >=1 has a sensitivity of 0.92 and specificity of 0.38.

• A score >= 2 has a sensitivity of 0.78 and specificity of 0.64.

• A score >= 3 has a sensitivity of 0.68 and specificity of 0.74.

 

Performance:

• The area under the ROC curve is 0.76.


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