Beppu et al reported a nomogram for predicting disease-free survival (DFS) after resection of colorectal liver metastases. This can help to identify a patient who may benefit from more aggressive or novel therapy. The authors are from multiple institutions in Japan with the authors belonging to the Japanese Society of Hepato-Biliary-Pancreatic Surgery.
Patient selection: status/post resection of colorectal liver metastases
Parameters:
(1) synchronous metastases
(2) primary lymph node status
(3) number of metastases
(4) largest tumor diameter in cm
(5) extrahepatic metastases at the time of liver surgery
(6) preoperative CA19-9 in ng/mL
Parameter
Finding
Points
synchronous metastases
no
0
yes
3
primary lymph node metastases
no
0
yes
3
number of liver metastases
1
0
2 to 4
4
>= 5
9
largest diameter
<= 5 cm
0
> 5 cm
2
extrahepatic metastases
no
0
yes
4
preoperative CA19-9
<= 100 ng/mL
0
> 100 ng/mL
4
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 25
Total Score
5-Year Disease-Free Survival
0
53 months
1-5
40 months
6-10
27.9 months
11-15
9.8 months
16-25
2.5 months
To read more or access our algorithms and calculators, please log in or register.
