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Nomogram of Pathak et al for Significant Hyperbilirubinemia in a North Indian Neonate

Description

Pathak et al developed a nomogram to identify a north Indian neonate at risk for significant hyperbilirubinemia. This can help to identify a neonate who may need more aggressive management. The authors are from Government Medical College in Chandigarh, India.


 

Patient selection: neonate from north India

 

Outcome: significant hyperbilirubinemia with need for phototherapy

 

Parameters:

(1) time since birth (from 6 to 200 hours)

(2) predischarge serum total bilirubin in mg/dL

 

Nomogram shows 3 risk lines:

(1) 40th percentile

(2) 75th percentile

(3) 95th percentile

Zone

Risk Group

< 40th percentile

low risk

40th to 74th

low-intermediate

75th to 94th

intermediate-high

>= 95th percentile

high risk

 

 

Hours

95th percentile

6 to 87.5

(-0.000939 * ((hours)^2)) + (0.1683 * (hours)) + 8.973

87.5 to 112.5

(-0.000163 * ((hours)^2)) + (0.008354 * (hours)) + 16.91

112.5 to 200

(0.000181 * ((hours)^2)) - (0.08449 * (hours)) + 23.03

 

 

Hours

75th percentile

6 to 87.5

(-0.000921 * ((hours)^2)) + (0.1682 * (hours)) + 5.965

87.5 to 112.5

(-0.000233 * ((hours)^2)) + (0.02312 * (hours)) + 13.28

112.5 to 200

(0.000162 * ((hours)^2)) - (0.07892 * (hours)) + 19.73

 

 

Hours

40th percentile

6 to 75

(-0.000879 * ((hours)^2)) + (0.1650 * (hours)) + 3.325

75 to 112.5

(-0.000245 * ((hours)^2)) + (0.02936 * (hours)) + 9.906

112.5 to 200

(0.000109 * ((hours)^2)) - (0.06041 * (hours)) + 15.41

 


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Specialty

ICD-10