Wang et al reported a nomogram for preoperative diagnosis of biliary atresia in an infant. The authors are from Beijing Children's Hospital.
Patient selection: infant less than 70 days of age with jaundice
Parameters:
(1) age in days, from 0 to 70 days
(2) hepatic elasticity in kPa, from 0 to 45
(3) gallbladder morphology
points for age =
= 11.3 - (0.161 * (score))
points for hepatic elasticity =
= 2.222 * (elasticity in kPa
|
Gallbladder Morphology
|
Points
|
|
normal
|
0
|
|
abnormal
|
16.1
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 127.4
value of X =
= (0.3166 * (score)) - 12.73
probability of biliary atresia =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.94.
