Zhang et al reported a nomogram for predicting severe infection in a child with adenovirus pneumonia. The authors are from Nanjing Medical University in China.
Patient selection: child with adenovirus pneumonia
Parameters:
(1) respiratory rate in breaths per minute
(2) percent neutrophils in the differential count
(3) percent lymphocytes in the differential count
(4) serum LDH in IU/L, from 0 to 2,400
points for respiratory rate =
= (0.6349 * (rate)) - 9.5229
points for percent neutrophils =
= 97.065 - (1.0785 * (percent))
points for percent lymphocytes =
= 112.5 - (1.25 * (percent))
points for serum LDH =
= 0.0102 * (LDH)
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 233.07
value of X =
= (0.2522 * (score)) - 29.85
probability of severe pneumonia =
= 1 / (1 + EXP((-1) * X))
Performance:
• The authors claim an area under the ROC curve of 0.94.