NOTE: The name NTDT-PRO is copyrighted.
Patient selection: non-transfusion dependent thalassemia
Outcome: health-related quality of life based on anemia-related symptoms
Symptoms:
(1) tiredness without physical activity
(2) tiredness with physical activity
(3) shortness of breath without physical activity
(4) shortness of breath with physical activity
(5) weakness without physical activity
(6) weakness with physical activity
Each item is graded on a 10 cm VAS scale (0 for none, 10 for extreme).
Findings are summarized into 2 concepts:
(1) tiredness/weakness
(2) shortness of breath
Other factors initially included but removed:
(1) worst pain
(2) ability to concentrate
(3) headaches
(4) pallor
