Rosenberg et al developed a risk score for detecting nosomial sepsis in a preterm infant from a low-resource setting. The authors are from the Johns Hopkins University in Baltimore.
Patient selection: preterm infant <= 33 weeks gestation
Clinical signs:
(1) pallor
(2) apnea
(3) hepatomegaly
(4) jaundice
(5) lethargy
The presence of one or more of these clinical signs was associated with sepsis.
Performance:
• The sensitivity was 77%.
• The area under the ROC curve was 70%. The positive predictive value is 65%.
• The test can be used for clinical screening, but in light of the sensitivity additional testing would be needed to find all septic patients.
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Specialty: Pedatrics, Infectious Diseases
ICD-10: ,
