Description

Noble at el reported the NUn score for predicting complications following esophageal resection. This can help to identify a patient who may benefit from more aggressive management. The authors are from the South Coast Cancer Collaboration-Oesophago-Gastric (SC-OG). The name of the score may be derived from the names of two of the authors.


 

Patient selection: esophageal resection

 

Outcome: major complications including anastomotic leak and death

 

Parameters determined on postoperative day 4:

(1) CRP in mg/L

(2) white blood cell count (WCC) in 10^9/L

(3) serum albumin in g/L

 

NUn score =

= (0.005 * (CRP)) + (0.186 * (WCC)) - (0.174 * (albumin)) + 11.3894

 

where:

• A low albumin is usually associated with worst prognosis. This score seems to say that a high albumin is worse.

 

Interpretation:

• A score > 10 was associated with major complications.

 

Performance:

• The score was found to have a sensitivity of 95% and specificity of 49% (detected most cases but had a high false positive rate) with a diagnostic accuracy of 0.801.

• Findlay et al performed a validation study and did not think that the score showed clinical utility.

 


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